Translational Research Cancer Centers Consortium

Meeting Agenda

Accreditation

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Wayne State University School of Medicine and the Translational Research Cancer Center Consortium (TRCCC). The Wayne State University School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

The Wayne State University School of Medicine designates this live activity for a maximum of 13.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.”

Meeting Agenda

Wednesday, February 22, 2012

2:00-6:00 pm - Registration (outside Grand Ballroom)

4:30 – 5:00 pm - Welcome Session for Advocates (Chestnut Room)

Maureen Meldrum, Karmanos Cancer Institute
Ruth Modzelewski, Ph.D., Breast Cancer Survivor
Wei-Zen Wei, Ph.D, Karmanos Cancer Institute and Wayne State School of Medicine
Pawel Kalinski, M.D., Ph.D, University of Pittsburgh Cancer Center
Session description

6:00 – 6:05 pm - Welcome by Meeting Co-Chairs (Grand Ballroom)

Wei-Zen Wei, Ph.D, Karmanos Cancer Institute and Wayne State School of Medicine
Lawrence Lum, M.D., DSC, Karmanos Cancer Institute and Wayne State School of Medicine

6:05 - 6:15 pm - Welcome Address (Grand Ballroom)

Ann Schwartz, Ph.D, Karmanos Cancer Institute and Wayne State School of Medicine

6:15– 6:20 pm - Introduction of Keynote Speaker (Grand Ballroom)

Pawel Kalinski, M.D., Ph.D, University of Pittsburgh Cancer Center

6:20 – 7:20 pm - Keynote address: "Chemokines in Cancer-Related Inflammation"

Alberto Mantovani, M.D., University of Milan, Italy

7:30 pm - Welcome Reception (Grand Ballroom)

Thursday, February 23, 2012

8:00 am - Registration (Grand Ballroom)

8:30 am - Symposium I - Recent Development in Cancer Vaccines (Grand Ballroom)
Chair: Michael Lotze, MD, University of Pittsburgh Cancer Center

8:30 - 9:10 am

Phase II study of dendritic cell vaccine vs poxvector vaccine for resected hepatic metastases of colorectal cancer

Michael Morse, M.D., Duke University

9:10 - 9:50 am

Dissecting the role of sunitinib in reversing immune tolerance to hepatocellular cancer

Kevin Staveley-O'Carroll, M.D., Ph.D., Penn State Hershey Cancer Center

9:50 - 10:30 am

Combination HER-2 vaccine and VEGF peptide therapeutic strategies for solid tumors including breast and ovarian cancers

Pravin Kaumaya, Ph.D, Ohio State University Cancer Center

10:30 - 11:00 am - COFFEE BREAK

	11:00 - 11:40 am	Development of immune protection against breast cancer Vincent Tuohy, Ph.D., Cleveland Clinic, Case Comprehensive Cancer Center
	11:40 am - 12:20 pm	Development of more rational and effective adjuvant therapy for melanoma John M. Kirkwood, M.D., University of Pittsburgh Cancer Center

12:00 – 2:00 pm - LUNCH SESSIONS (Box lunch available in Seasons Room)

12:45 pm

Collaboration with Industry - "Her-2 DNA vaccine Trials - IDN 6439-RHUT" (Wintergreen Room. No CME Credit)

Chair: Lawrence Lum, M.D., D.Sc., Karmanos Cancer Institute

Speakers: Federical Cavallo, Ph.D., University of Torino, Italy & Ulka Vaishampayan, M.D., Karmanos Cancer Institute

1:00 pm

Junior Investigator Froup Meeting
(Sunburst Room. NO CME Credit)

Organizer: Kathleen Kokulus, PhD Candidate, Roswell Park Cancer Institute

2:30 – 3:15 pm - Workshops (Parallel Sessions)

Block I

Cancer Vaccine and Immune Regulation #1
(Snowflake Room)

Federica Cavallo, Ph.D, University of Torino, Italy

Soldano Ferrone, M.D., Ph.D., University of Pittsburgh Medical Center

View Abstract Assignments

Block II

Optimization Strategies for Adoptive T Cell Therapy
(Sunburst Room)

Robert Vonderheide, M.D., DPhil, Abramson Cancer Center

Gregory Beatty, M.D., Ph.D., Abramson Cancer Center

View Abstract Assignments

Block III

Innate Immunity and Tumor Microenvironment
(Wintergreen Room)

Laura Gibson, Ph.D, Mary Babb Randolph Cancer Center, WVU

Elizabeth Repasky, Ph.D, Roswell Park Cancer Institute

View Abstract Assignments

3:15 - 3:30 pm - COFFEE BREAK

3:45 – 4:45 pm - Workshops (Parallel Sessions)

Block IV

Novel Therapies (Sunburst Room)

William Tse, M.D., Mary Babb Randolph cancer Center, WVU

Kelvin Lee, M.D., Roswell Park Cancer Institute

View Abstract Assignments

Block V

GI and Urologic Malignancy (Snowflake Room)

Pawel Kalinski, M.D., Ph.D., University of Pittsburgh Cancer Institute

William Petros, PharmD, FCCP, Mary Babb Randolph Cancer Center, WVU
View Abstract Assignments

Block VI

Hematologic Malignancy (Wintergreen Room)

Lawrence Lum, M.D., DSC, Karmanos Cancer Institute, Wayne State School of Medicine

Thomas Loughran, M.D., Penn State Hershey Cancer Center

View Abstract Assignments

5:00 – 7:00 pm - Posters and Reception (Grand Ballroom)

Friday, February 24, 2012

8:30 am – 12:20 pm - Symposium II - Immune Regulation in Cancer (Grand Ballroom)
Chair: Wei-Zen Wei, PhD, Karmanos Cancer Institute

	8:30 - 9:10 AM	T cells instigate immune suppression within the tumor Jonathan Bramson, Ph.D, McMaster University, Hamilton, Canada
	9:10 - 9:50 AM	CD40 Therapy for Cancer Robert Vonderheide, M.D., DPhil, Abramson Cancer Center
	9:50 – 10:30 am	Targeting HDACs as a new strategy for GVHD prevention Pavan Reddy, M.D., University of Michigan Comprehensive Cancer Center

10:30 - 11:00 am - COFFEE BREAK

	11:00 - 11:40 am	Lung Cancer Susceptibility and Markers of Inflammation Ann Schwartz, Ph.D, Karmanos Cancer Institute
	11:40 am - 12:20 pm	Regulating mTOR for tumor immunity Protul Shrikant, Ph.D, Roswell Park Cancer Institute