Translational Research Cancer Centers Consortium

Translational Research Cancer Centers Consortium

Expediting Progress in Cancer Immunotherapy

Copyright Translational Research Cancer Centers Consortium

2016 Young Investigator Award Winners

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2016 TRCCC Annual Meeting Photos

Session 1: Tumor Microenvironment

  1. Abigail Overacre, University of Pittsburgh - NEUROPILIN-1 ENFORCES TREG STABILITY AND FUNCTION IN THE TUMOR MICROENVIRONMENT
  2. Colleen Netherby, Roswell Park Cancer Institute - INTERFERON REGULATORY FACTOR-8 (IRF8) RESTORES THE MYELOID BALANCE IN CANCER


Session 2:‚Äč Cell Therapies

  1. Joanne Hammill, McMaster University - A NOVEL XENOGRAFT MODEL OF CHIMERIC ANTIGEN RECEPTOR-MEDIATED OFF-TUMOR TOXICITY
  2. Christopher Helsenm, McMaster University - T-CELL ANTIGEN COUPLER (TAC) ENGINEERED T CELLS DEMONSTRATE EFFICACY AGAINST SOLID TUMORS


Session 3: Translational and Clinical Cancer Studies

  1. Jessica Chacon, University of Pennsylvania - FIRST IN-DEPTH INVESTIGATION OF MULTIPLE INHIBITORY MOLECULE EXPRESSION BY BONA FIDE TUMOR-REACTIVE T CELLS IN OVARIAN CANCER.
  2. Yeshavantha Kumar Bansavadi-Siddegowda, The Ohio State University - PRMT5-PTEN MOLECULAR PATHWAY REGULATES SENESCENCE AND SELF-RENEWAL OF GLIOBLASTOMA STEM-LIKE CELLS


Session 4: Tumor Microenvironment #2

  1. Jenessa Smith, University of Pennsylvania - FEASIBILITY AND SAFETY OF CCD20 RNA CAR-BEARING T CELL THERAPY FOR THE TREATMENT OF CANINE B CELL MALIGNANCIES
  2. Gary Kohanbash, University of Pittsburgh - IDH MUTATION-INDUCED SUPPRESSION OF TYPE-1 ANTI-GLIOMA IMMUNE RESPONSES


Session 5: Viral therapies/ Vaccines and Model Systems

  1. Heather Gibson, Karmanos Cancer Institute - IN SITU IMMUNE IMAGING TO MONITOR THE IMPACT OF IMMUNOTHERAPY
  2. Kellie Haworth, Nationwide Children's Hospital - ONCOLYTIC VIROTHERAPY ENHANCES GD2-DIRECTED CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY IN GD2-EXPRESSING PEDIATRIC SOLID TUMOR XENOGRAFT MODELS      2. Keisuke Watanabe, University of Pennsylvania - ONCOLYTIC ADENOVIRUS ARMED WITH CYTOKINES ENHANCES CAR-T CELL EFFICACY IN PANCREATIC TUMOR MODEL


Session 6: Emerging Therapies

  1. Steven Jones, Karmanos Cancer Institute - FOLATE RECEPTOR TARGETED DELIVERY OF SIRNA AND PACLITAXEL TO OVARIAN CANCER CELLS VIA FOLATE CONJUGATED TRIBLOCK COPOLYMER TO OVERCOME TLR4 DRIVEN CHEMOTHERAPY RESISTANCE
  2. Mark Bucsek, Roswell Park Cancer Institute - ADRENERGIC SIGNALING MEDIATES IMMUNE SUPPRESSION INDUCED BY COOL HOUSING TEMPERATURES FOR LABORATORY MICE


Poster 

  1. Jenessa Smith, University of Pennsylvania - FEASIBILITY AND SAFETY OF CCD20 RNA CAR-BEARING T CELL THERAPY FOR THE TREATMENT OF CANINE B CELL MALIGNANCIES
  2. Colleen Netherby, Roswell Park Cancer Institute - INTERFERON REGULATORY FACTOR-8 (IRF8) RESTORES THE MYELOID BALANCE IN CANCER